Debutyldronedarone D6 hydrochloride |
رقم الكتالوجGC60746 |
ديبوتيلدرونيدارون D6 هيدروكلوريد (SR35021 D6 هيدروكلوريد) هو الديوتيريوم المسمى ديبوتيلدرونيدارون
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Cas No.: 1346598-70-6
Sample solution is provided at 25 µL, 10mM.
Debutyldronedarone D6 hydrochloride (SR35021 D6 hydrochloride) is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone in humans. Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent[1][2].
[1]. Cen Xie, et al. Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.J Chromatogr B Analyt Technol Biomed Life Sci [2]. Marina Santos, et al.Synthesis and characterization of new related substances of the antiarrhythmic drug dronedarone hydrochloride. J Pharm Biomed Anal. 2015 Oct 10;114:441-6.
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