Delavirdine mesylate (Synonyms: U 90152 mesylate; BHAP-U 90152 mesylate) |
| رقم الكتالوجGC15452 |
Delavirdine (U 90152) mesylate هو مثبط قوي وعالي التحديد وفعال عن طريق الفم غير النوكليوزيد العكسي (NNRTI)
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Cas No.: 147221-93-0
Sample solution is provided at 25 µL, 10mM.
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Delavirdine mesylate (U 90152 mesylate) is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor (NNRTI) of HIV-1.
References:
[1]. Dueweke TJ, et al. U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication. Antimicrob Agents Chemother. 1993 May;37(5):1127-31.
[2]. Voorman RL, et al. Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6. Drug Metab Dispos. 2001 Jan;29(1):41-7.
[3]. Shelton MJ, et al. Pharmacokinetics of ritonavir and delavirdine in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother. 2003 May;47(5):1694-9.
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