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DMTr-LNA-5MeU-3-CED-phosphoramidite

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DMTr-LNA-5MeU-3-CED-phosphoramidite هو مشتق من النيوكليوزيد.

Products are for research use only. Not for human use. We do not sell to patients.

DMTr-LNA-5MeU-3-CED-phosphoramidite التركيب الكيميائي

Cas No.: 206055-75-6

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
95٫00
متوفر
100mg
86٫00
متوفر
250mg
145٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of DMTr-LNA-5MeU-3-CED-phosphoramidite

DMTr-LNA-5MeU-3-CED-phosphoramidite is a nucleoside derivative[1].

[1]. Kumar P, et al. Locked nucleic acid (LNA) enhances binding affinity of triazole-linked DNA towards RNA. Chem Commun (Camb). 2017 Aug 3;53(63):8910-8913.

Chemical Properties of DMTr-LNA-5MeU-3-CED-phosphoramidite

Cas No. 206055-75-6 SDF
Formula C41H49N4O9P M.Wt 772.82
الذوبان DMSO : 250 mg/mL (323.49 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of DMTr-LNA-5MeU-3-CED-phosphoramidite

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.294 mL 6.4698 mL 12.9396 mL
5 mM 258.8 μL 1.294 mL 2.5879 mL
10 mM 129.4 μL 647 μL 1.294 mL
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** عند إعداد حلول المخزون، دائمًا استخدم الوزن الجزيئي الخاص بالدفعة للمنتج على ملصق القارورة MSDS / CoA (متوفر عبر الإنترنت).

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In vivo Formulation Calculator (Clear solution) of DMTr-LNA-5MeU-3-CED-phosphoramidite

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for DMTr-LNA-5MeU-3-CED-phosphoramidite

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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