Eleutheroside B1 |
| رقم الكتالوجGC63987 |
إليوثيروسيد B1 ، مركب كومارين ، له طيف واسع من فعالية فيروس الأنفلونزا البشرية ، بقيمة IC50 تبلغ 64-125 ميكروغرام / مل
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 16845-16-2
Sample solution is provided at 25 µL, 10mM.
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Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1].
Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells[1].
[1]. Yan W, et al. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation.Int J Mol Med. 2018 Nov;42(5):2776-2792.
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