Epitinib succinate (Synonyms: HMPL-813 succinate) |
| رقم الكتالوجGC62384 |
Epitinib succinate هو عامل نمو جلدي نشط وانتقائي لمستقبلات التيروزين كيناز (EGFR-TKI) مصمم لاختراق الدماغ الأمثليمكن استخدام Epitinib succinate في أبحاث السرطان
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Cas No.: 2252334-12-4
Sample solution is provided at 25 µL, 10mM.
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Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer[1][2].
Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration[1][2].
[1]. Zhou et al. The safety profile of a selective EGFR TKI epitinib (HMPL-813) in patients with advanced solid tumors and preliminary clinical efficacy in EGFRm+ NSCLC patients with brain metastasis. Journal of Clinical Oncology 2016 34:15_suppl, e20502-e20502
[2]. Zhou et al. Phase I study of the safety and pharmacokinetics of epitinib, an oral EGFR tyrosine kinase inhibitor, in patients with advanced solid tumors. Journal of Clinical Oncology 2013 31:15_suppl, e19042-e19042
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