Erlotinib D6 (Synonyms: CP-358774-d6; NSC 718781-d6; OSI-774-d6) |
رقم الكتالوجGC60154 |
Erlotinib D6 (CP-358774 D6) هو الديوتيريوم المسمى Erlotinib (CP-358774). Erlotinib هو مثبط يعمل بشكل مباشر مع مثبط EGFR التيروزين كيناز مع IC50 من 2 نانومتر لـ EGFR البشري.
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Cas No.: 1034651-23-4
Sample solution is provided at 25 µL, 10mM.
Erlotinib D6 (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1].
[1]. Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997, 57(21), 4838-4848.
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