Fluticasone furoate (Synonyms: GSK685698, GW 685698X) |
| رقم الكتالوجGC39222 |
فلوتيكاسون فوروات هو كورتيكوستيرويد ثلاثي الفلور صناعي موضعي داخل الأنف وذو تقارب مُحسَّن مع Kd 0.3 نانومتر
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Cas No.: 397864-44-7
Sample solution is provided at 25 µL, 10mM.
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Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment[1][2].
[1]. Giavina-Bianchi P, et al. Fluticasone furoate nasal spray in the treatment of allergic rhinitis. Ther Clin Risk Manag. 2008 Apr;4(2):465-72. [2]. Alizadeh Z, et al. Asthma phenotypes and T-bet protein expression in cells treated with Fluticasone Furoate/Vilanterol. Pulm Pharmacol Ther. 2020 Feb;60:101886.
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