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Folic acid disodium

رقم الكتالوجGC71505 Copy One-Click Copy Product Info

Folic acid disodium (فيتامين B9 ثنائي الصوديوم ؛ ثنائي الصوديوم فيتامين م) هو ملح ثنائي الصوديوم النشط عن طريق الفم من حمض الفوليك بمعدل إذابة داخلي (IDR) يبلغ 4.96/105 غم/ث.

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Folic acid disodium التركيب الكيميائي

Cas No.: 29704-76-5

الحجم السعر المخزون الكميّة
25 mg
90٫00
متوفر
50 mg
144٫00
متوفر
100 mg
234٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of Folic acid disodium

Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid with an intrinsic dissolution rate (IDR) of 4.96·105 g/s. Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia.

References:
[1]. Braga D., et al., Folic Acid in the Solid State: A Synergistic Computational, Spectroscopic, and Structural Approach, Crystal Growth & Design, 2016, 16, 4, 2218–222.
[2]. Shulpekova Y, et al., The Concept of Folic Acid in Health and Disease. Molecules. 2021 Jun 18;26(12):3731.

Chemical Properties of Folic acid disodium

Cas No. 29704-76-5 SDF
Formula C19H17N7Na2O6 M.Wt 485.36
الذوبان H2O : ≥ 100 mg/mL (206.03 mM) Storage 4°C, sealed storage, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Folic acid disodium

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0603 mL 10.3016 mL 20.6033 mL
5 mM 412.1 μL 2.0603 mL 4.1207 mL
10 mM 206 μL 1.0302 mL 2.0603 mL
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In vivo Formulation Calculator (Clear solution) of Folic acid disodium

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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