Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH |
| رقم الكتالوجGA20454 |
Internally quenched fluorogenic peptide substrate containing anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 174838-79-0
Sample solution is provided at 25 µL, 10mM.
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Internally quenched fluorogenic peptide substrate containing anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher). The sequence Abz-RVKRGLAY(NO₂)D is based on the sequence of hemagglutinin. The FRET substrate is efficiently cleaved by furin, a subtilisin-like eukaryotic serine endoprotease with Km = 3.8 µM and kcat = 29.3 s-¹ (kcat/Km = 7’710’000 M-¹s-¹). Its kcat/Km value is over 2000-fold higher than that of the commonly used substrate Boc-Arg-Val-Arg-Arg-AMC. FRET Substrate for the basic residue-specific yeast aspartyl protease yapsin 1.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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