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H-Pro-Tyr-OH

رقم الكتالوجGA22872 Copy One-Click Copy Product Info

H-Pro-Tyr-OH is a dipeptide that can be cyclized and is used for membrane analysis.

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H-Pro-Tyr-OH التركيب الكيميائي

Cas No.: 19786-36-8

الحجم السعر المخزون الكميّة
1g
586٫00
متوفر
5g
2046٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.



Description of H-Pro-Tyr-OH

H-Pro-Tyr-OH is a dipeptide that can be cyclized and is used for membrane analysis[1]. Peptides containing the H-Pro-Tyr-OH fragment have a low-energy conformation and can be used in multiple molecular dynamics simulation experiments[2]. H-Pro-Tyr-OH is widely used as a model compound for analyzing molecular conformation in circular dichroism experiments[3].

References:
[1] Matsufuji H, Matsui T, Ohshige S, et al. Antihypertensive effects of angiotensin fragments in SHR[J]. Bioscience, biotechnology, and biochemistry, 1995, 59(8): 1398-1401.
[2] Nardi F, Kemmink J, Sattler M, et al. The cisproline (i− 1)-aromatic (i) interaction: Folding of the Ala-cisPro-Tyr peptide characterized by NMR and theoretical approaches[J]. Journal of biomolecular NMR, 2000, 17(1): 63-77.
[3] Wierzchowski K L, Majcher K, Poznański J. CD investigations on conformation of HX-(Pro) nY-OH peptides (X= Trp, Tyr; Y= Tyr, Met); models for intramolecular long range electron transfer[J]. Acta Biochimica Polonica, 1995, 42(2): 259-268.

Chemical Properties of H-Pro-Tyr-OH

Cas No. 19786-36-8 SDF
Formula C14H18N2O4 M.Wt 278.31
الذوبان Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of H-Pro-Tyr-OH

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.5931 mL 17.9656 mL 35.9312 mL
5 mM 718.6 μL 3.5931 mL 7.1862 mL
10 mM 359.3 μL 1.7966 mL 3.5931 mL
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In vivo Formulation Calculator (Clear solution) of H-Pro-Tyr-OH

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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