Phenylacetyl-(D-Arg²·²⁸,p-chloro-Phe⁶,Homoarg⁹·²⁹,Tyr(Me)¹⁰,Abu¹⁵,Nle²⁷)-GRF (1-29) amide (human) |
| رقم الكتالوجGA23360 |
JV-1-38 exhibited antagonistic activity against human growth hormone-releasing hormone (hGH-RH) slightly less potent than JV-1-36 (H-4884) both in vitro and in vivo but proved to be very long-acting in vivo, suppressing the GH-RH induced GH release even after 60 min. Antagonists of this structure are possible candidates for clinical application in the treatment of cancers dependent on insulin-like growth factors I and II.
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Cas No.: 221377-79-3
Sample solution is provided at 25 µL, 10mM.
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JV-1-38 exhibited antagonistic activity against human growth hormone-releasing hormone (hGH-RH) slightly less potent than JV-1-36 both in vitro and in vivo but proved to be very long-acting in vivo, suppressing the GH-RH induced GH release even after 6
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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