(+)-CBI-CDPI2 |
رقم الكتالوجGC34956 |
(+) - CBI-CDPI2 هو نظير وظيفي محسن لـ CC-1065(+) - CBI-CDPI1 هو عامل مؤلكل للحمض النووي(+) - CBI-CDPI2 هو توكسين دواء مترافق مع الأجسام المضادة (ADCs)
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Cas No.: 128300-15-2
Sample solution is provided at 25 µL, 10mM.
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody drug conjugates (ADCs) toxin.
[1]. Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35.
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