2-Hydroxy atorvastatin calcium salt (Synonyms: o-hydroxy Atorvastatin, ortho-hydroxy Atorvastatin, BMS 243887-01, PD 152873) |
| رقم الكتالوجGC35090 |
2-هيدروكسي أتورفاستاتين ملح كالسيوم هو مستقلب هيدروكسي من ملح الكالسيوم أتورفاستاتين
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Cas No.: 265989-46-6
Sample solution is provided at 25 µL, 10mM.
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2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.
[1]. Borek-DohalskÝ V, et al. Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study. Anal Bioanal Chem. 2006 Sep;386(2):275-85.
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