DMT1 blocker 1 |
رقم الكتالوجGC35885 |
مانع DMT1 1 هو مانع للناقل المعدني ثنائي التكافؤ 1 (DMT1) مع IC بمقدار 0.64 ميكرومتر ، ومن المتوقع أن يمنع امتصاص الحديد بواسطة الخلايا المعوية في الجسم الحي
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Cas No.: 1354790-56-9
Sample solution is provided at 25 µL, 10mM.
DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo[1]. IC50: 0.64 μM (DMT1 blocker 1)[1]
[1]. Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.
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