Ganoderic acid C2 |
رقم الكتالوجGC36117 |
حمض الجانوديريك C2 هو ترايتيربينويد النشط بيولوجيًا في غانوديرما لوسيدوميمتلك حمض الجانوديريك C2 النشاط الحيوي المضاد للأورام ، ومضادات الهيستامين ، والتأثيرات السامة للخلايا والشيخوخةيُظهر حمض الجانوديريك C2 نشاطًا مثبطًا عاليًا ضد اختزال ألدوز عدسات الجرذ (RLAR) مع IC 50 من 3.8 ميكرومتر
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Cas No.: 103773-62-2
Sample solution is provided at 25 µL, 10mM.
Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM[1][2]. IC50: 3.8 µM (RLAR)[2]
[1]. Guo XY, et al. l characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73. [2]. Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76(15):1691-3.
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