Odiparcil (Synonyms: SB-424323) |
| رقم الكتالوجGC36792 |
Odiparcil (SB-424323) هو نظير فعال عن طريق الفم بيتا-د-ثيوكسيلوسيد مع نشاط مضاد للتخثر المرتبط بتقليل مخاطر حدوث نزيف ضار
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 137215-12-4
Sample solution is provided at 25 µL, 10mM.
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Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2]. Thrombin[2]
[1]. Myers AL, et al. Characterization of total plasma glycosaminoglycan levels in healthy volunteers following oral administration of a novel antithrombotic odiparcil with aspirin or enoxaparin. J Clin Pharmacol. 2008 Oct;48(10):1158-70 [2]. Levy JH, et al. Novel oral anticoagulants: implications in the perioperative setting. Anesthesiology. 2010 Sep;113(3):726-45.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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