Olinciguat (Synonyms: IW-1701) |
| رقم الكتالوجGC36801 |
Olinciguat (IW-1701) هو محفز لانزيم الجوانيلات الفموي (sGC) مع تحفيز يعتمد على التركيز لـ sGC في الجرذان المنقى ومقايسات الإنزيم البشري ومقايسة الخلية الكاملة
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Cas No.: 1628732-62-6
Sample solution is provided at 25 µL, 10mM.
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Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay[1].
[1]. Buys ES, et al. Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential. Nitric Oxide. 2018 Aug 1;78:72-80.
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