Scyllo-Inositol (Synonyms: ELND 005, scyllo-Cyclohexanehexol) |
| رقم الكتالوجGC37610 |
Scyllo-Inositol ، مثبط أميلويد ، يحتمل أن يثبط تراكم α-synuclein
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 488-59-5
Sample solution is provided at 25 µL, 10mM.
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Scyllo-Inositol, an amyloid inhibitor, potentialy inhibits α-synuclein aggregation. Scyllo-Inositol stabilizes a non-fibrillar non-toxic form of amyloid-β peptide (Aβ42) in vitro, reverses cognitive deficits, and reduces synaptic toxicity and loweres amyloid plaques in an Alzheimer's disease mouse model[1].
[1]. Ibrahim T, et al. α-Synuclein aggregation, seeding and inhibition by scyllo-inositol. Biochem Biophys Res Commun. 2016 Jan 15;469(3):529-34.
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