YKL-06-061 |
| رقم الكتالوجGC37951 |
YKL-06-061 هو مثبط قوي ، انتقائي ، من الجيل الثاني للكيناز المحفز بالملح (SIK) بقيم IC50 تبلغ 6.56 نانومتر / 1.77 نانومتر / 20.5 نانومتر لـ SIK1 / 2/3 ، على التوالي
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Cas No.: 2172617-15-9
Sample solution is provided at 25 µL, 10mM.
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YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1]. IC50: 6.56 nM/1.77 nM/20.5 nM (SIK1/2/3)[1].
[1]. Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.
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