الصفحة الرئيسية>>Signaling Pathways>> TGF-β / Smad Signaling>> PKC>>Daphnoretin

Daphnoretin (Synonyms: NSC 291852)

رقم الكتالوجGC38186

Daphnoretin (Dephnoretin) ، المعزول من Wikstroemia indica ، يمتلك نشاطًا مضادًا للفيروسات

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Daphnoretin التركيب الكيميائي

Cas No.: 2034-69-7

الحجم السعر المخزون الكميّة
1mg
52٫00
متوفر
5mg
81٫00
متوفر
10mg
143٫00
متوفر
20mg
235٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description of Daphnoretin

Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity[1]. Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst[2].

[1]. Ho WS, et al. Antiviral activity of daphnoretin isolated from Wikstroemia indica. Phytother Res. 2010 May;24(5):657-61. [2]. Wang JP, et al. Daphnoretin-induced respiratory burst in rat neutrophils is, probably, mainly through protein kinase C activation. Eur J Pharmacol. 1995 Feb 15;288(3):341-8.

Chemical Properties of Daphnoretin

Cas No. 2034-69-7 SDF
المرادفات NSC 291852
Canonical SMILES O=C1C(OC2=CC=C(C(O3)=C2)C=CC3=O)=CC4=CC(OC)=C(O)C=C4O1
Formula C19H12O7 M.Wt 352.29
الذوبان DMF: 25 mg/ml,DMSO: 25 mg/ml,Ethanol: partially soluble,PBS (pH >10.2): Partially soluble Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Daphnoretin

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8386 mL 14.1929 mL 28.3857 mL
5 mM 0.5677 mL 2.8386 mL 5.6771 mL
10 mM 0.2839 mL 1.4193 mL 2.8386 mL
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In vivo Formulation Calculator (Clear solution) of Daphnoretin

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 12 reference(s) in Google Scholar.)

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