Scoparone (Synonyms: Aesculetin dimethyl ether, 6,7-Dimethoxycoumarin, 6,7-Dimethylesculetin, Escoparone) |
| رقم الكتالوجGC38420 |
A coumarin with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 120-08-1
Sample solution is provided at 25 µL, 10mM.
Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].
Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM[1].
Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats[1]. Animal Model: Chronic Pancreatitis (CP) Rat Models[1]
[1]. Xu M, et al. Scoparone Protects Against Pancreatic Fibrosis via TGF-β/Smad Signaling in Rats. Cell Physiol Biochem. 2016;40(1-2):277-286. Epub 2016 Nov 18.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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