GDC-0927 Racemate (SRN-927 Racemate) (Synonyms: SRN-927 Racemate) |
| رقم الكتالوجGC33193 |
GDC-0927 Racemate (SRN-927 Racemate) (SRN-927 Racemate) هو مادة تحلل مستقبلات هرمون الاستروجين ، وتثبط بشكل فعال ER-α ؛ النشاط ، مع IC 50 من 0.2 نانومتر ، ويستخدم في البحث عن الأمراض المرتبطة ER.
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Cas No.: 1443983-36-5
Sample solution is provided at 25 µL, 10mM.
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GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.
GDC-0927 Racemate (Example 1) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. GDC-0927 Racemate reduces the viability of MCF7 cells with an IC50 of 0.21 nM[1].
[1]. Mehmet Kahraman, et al. Estrogen receptor modulator and uses thereof. WO2014205138A1.
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