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L-6424

رقم الكتالوجGC70494 Copy One-Click Copy Product Info

L-6424 يثبط ارتباط T3 مع α1-T3R و β1-T3R.

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L-6424 التركيب الكيميائي

Cas No.: 147030-50-0

الحجم السعر المخزون الكميّة
5 mg
171٫00
متوفر
10 mg
266٫00
متوفر
25 mg
531٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of L-6424

L-6424 inhibits T3 binding to α1-T3R and β1-T3R.

References:
[1]. H C van Beeren, et al. Structure-function relationship of the inhibition of the 3,5,3'-triiodothyronine binding to the alpha1- and beta1-thyroid hormone receptor by amiodarone analogs. Endocrinology. 1996 Jul;137(7):2807-14.

Chemical Properties of L-6424

Cas No. 147030-50-0 SDF
Formula C19H17IO3 M.Wt 420.24
الذوبان Storage
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of L-6424

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.3796 mL 11.898 mL 23.7959 mL
5 mM 475.9 μL 2.3796 mL 4.7592 mL
10 mM 238 μL 1.1898 mL 2.3796 mL
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** عند إعداد حلول المخزون، دائمًا استخدم الوزن الجزيئي الخاص بالدفعة للمنتج على ملصق القارورة MSDS / CoA (متوفر عبر الإنترنت).

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In vivo Formulation Calculator (Clear solution) of L-6424

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for L-6424

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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