L-threo-PPMP (hydrochloride) (Synonyms: L-threo-1-phenyl-2-Palmitoylamino-3-morpholino-1-propanol) |
| رقم الكتالوجGC44087 |
L-threo-PPMP is an inhibitor of glucosylceramide synthetase and isomer of D-threo-PPMP.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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L-threo-PPMP is an inhibitor of glucosylceramide synthetase and isomer of D-threo-PPMP . It inhibits the growth of MCF-7, MDA-MB-468, and SK-BR-3 breast cancer cells (ED50s = 4, 7, and 6 μM, respectively) through damage of cell organelle membranes, increasing ceramide concentration, and induction of apoptosis.
Review for L-threo-PPMP (hydrochloride)
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
Review for L-threo-PPMP (hydrochloride)
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