Legumain inhibitor 1 |
| رقم الكتالوجGC62565 |
مثبط Legumain 1 هو مثبط قوي وانتقائي Legumain مع IC50 3.6 نانومتريمكن استخدام مثبط الليجومين 1 في أبحاث السرطان
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2361157-34-6
Sample solution is provided at 25 µL, 10mM.
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Legumain inhibitor 1 is a potent and selective Legumain inhibitor with an IC50 of 3.6 nM. Legumain inhibitor 1 can be used for cancer research[1].
Legumain inhibitor 1 (Compound 16i) shows high microsomal stability with half-life’s in excess of 8 h (mouse and human MICs; CLint > 3 µL/min/mg)[1][1].
[1]. Sharon L Eddie, et al. Identification and SAR exploration of a novel series of Legumain inhibitors. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1546-1548.
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