Milvexian (Synonyms: BMS-986177; JNJ-70033093) |
| رقم الكتالوجGC63873 |
Milvexian (BMS-986177) ، عامل فعال مضاد للتخثر ، هو مثبط متاح بيولوجيًا وعكسًا ومباشرًا للعامل XIa البشري والأرنب (FXIa) مع Ki 0.11 و 0.38 نانومتر على التوالي
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Cas No.: 1802425-99-5
Sample solution is provided at 25 µL, 10mM.
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Milvexian (BMS-986177), an effective antithrombotic agent, is an orally-bioavailable, reversible and direct inhibitor of human and rabbit factor XIa (FXIa) with Ki of 0.11, and 0.38 nM, respectively[1].
[1]. Wong P, et al. Small-Molecule Factor XIa Inhibitor, BMS-986177/JNJ-70033093, Prevents and Treats Arterial Thrombosis in Rabbits at Doses that Preserve Hemostasis [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1).
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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