Oleclumab |
رقم الكتالوجGC65470 |
Oleclumab (MEDI9447) هو جسم مضاد أحادي النسيلة IgG1Λ بشري مضاد لـ CD73 يثبط وظيفة CD73Oleclumab له نشاط مضاد للورم
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Cas No.: 1803176-05-7
Sample solution is provided at 25 µL, 10mM.
Oleclumab (MEDI9447) is a human IgG1Λ anti-CD73 monoclonal antibody that inhibits CD73 function. Oleclumab has an anti-tumor activity[1].
[1]. Roy S Herbst, et al. COAST: An Open-Label, Phase II, Multidrug Platform Study of Durvalumab Alone or in Combination With Oleclumab or Monalizumab in Patients With Unresectable, Stage III Non-Small-Cell Lung Cancer. J Clin Oncol. 2022 Apr 22;JCO2200227.
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