Omidenepag (Synonyms: UR-7276) |
| رقم الكتالوجGC61156 |
Omidenepag ، وهو شكل نشط دوائيا من Omidenepag Isopropyl ، هو ناهض مستقبلات EP2 انتقائية غير بروستانويد ، مع EC50 من 1.1 نانومتر
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Cas No.: 1187451-41-7
Sample solution is provided at 25 µL, 10mM.
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Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2[1].
[1]. Iwamura R, et al. Identification of a Selective, Non-Prostanoid EP2 Receptor Agonist for the Treatment of Glaucoma: Omidenepag and its Prodrug Omidenepag Isopropyl. J Med Chem. 2018 Aug 9;61(15):6869-6891.
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