PD-1/PD-L1 Inhibitor 3 (trifluoroacetate salt) (Synonyms: Programmed Cell Death 1/Programmed Cell Death-Ligand 1 Inhibitor 3) |
رقم الكتالوجGC52425 |
A PD-1/PD-L1 interaction inhibitor
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Sample solution is provided at 25 µL, 10mM.
PD-1/PD-L1 inhibitor 3 is a macrocyclic peptide inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1).1 It inhibits the PD-1/PD-L1 interaction in a time-resolved FRET (TR-FRET) assay (IC50 = 9 nM).
1.Miller, M.M., Mapelli, C., Allen, P., et al.Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions(2017)
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