(R)-Gyramide A (hydrochloride) (Synonyms: (R)-534F6) |
| رقم الكتالوجGC41717 |
(R) -Gyramide A (هيدروكلوريد) هو مثبط جرثومي للحمض النووي DNA يعطل نشاط الالتفاف الفائق بقيمة IC50 تبلغ 3.3 ميكرومتر.
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Cas No.: 1793050-70-0
Sample solution is provided at 25 µL, 10mM.
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(R)-Gyramide A is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 µM. It does not affect the closely related enzyme topoisomerase IV. (R)-Gyramide A demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs range from 10-80 µM).
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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