Raloxifene 6-Glucuronide (Synonyms: Ral-6-Gluc) |
| رقم الكتالوجGC44805 |
Raloxifene 6-glucuronide هو مستقلب أولي لـ Raloxifene
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Cas No.: 174264-50-7
Sample solution is provided at 25 µL, 10mM.
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Raloxifene 6-glucuronide is a metabolite of the selective estrogen receptor modulator raloxifene . It is formed from raloxifene via the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1 and UGT1A8. It binds to the estrogen receptor with an IC50 value of 290 nM. Unlike raloxifene, raloxifene 6-glucuronide does not inhibit the voltage-gated potassium channel Kv4.3.
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