Rubiadin-1-methyl ether (Synonyms: NSC 59063, RBM) |
رقم الكتالوجGC60331 |
Rubiadin-1-methyl ether هو أنثراكينون طبيعي معزول من Morinda officinalis How ، ويمنع ارتشاف العظم الناجم عن طريق تثبيط الفسفرة لـ NF-κB p65 وتدهور IκBα وكذلك انخفاض في الانتقال النووي لـ p65
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7460-43-7
Sample solution is provided at 25 µL, 10mM.
Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].
[1]. He YQ, et al. Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathway. Biochem Biophys Res Commun. 2018 Dec 2;506(4):927-931.
Average Rating: 5
(Based on Reviews and 13 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *