Sermorelin (trifluoroacetate salt) |
| رقم الكتالوجGC44883 |
Sermorelin is a 29-residue N-terminal analog of growth hormone-releasing hormone (GHRH) that retains the ability to stimulate growth hormone (GH) release.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Sermorelin is a 29-residue N-terminal analog of growth hormone-releasing hormone (GHRH) that retains the ability to stimulate growth hormone (GH) release. Sermorelin (1 μg/kg, i.v.) increases serum GH levels in rats by approximately 17% compared with saline control after 15 minutes. It also increases GH release in pigs when administered at a dose of 250 ng/kg. Sermorelin (1 μM) increases proliferation of NCI-H727 human bronchial carcinoid cells by 30% and increases vascular endothelial growth factor (VEGF) secretion. It increases phosphorylation of focal adhesion kinase (FAK) and expression of VEGF in A549 lung cancer cells when used at a concentration of 0.1 μM. Formulations containing sermorelin have been used to diagnose and treat growth hormone deficiency.
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