الصفحة الرئيسية>>Natural Products>>Shikalkin

Shikalkin (Synonyms: (±)-Alkannin, (±)-Shikonin, NSC 291845)

رقم الكتالوجGC49234 Copy One-Click Copy Product Info

يمتلك شيكالكين (شيكونين) نشاطًا مضادًا للورم. يتحايل شيكالكين (شيكونين) على مقاومة عقاقير السرطان عن طريق تحريض موت نخر.

Products are for research use only. Not for human use. We do not sell to patients.

Shikalkin التركيب الكيميائي

Cas No.: 54952-43-1

الحجم السعر المخزون الكميّة
5mg
25٫00
متوفر
10mg
68٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of Shikalkin

Shikalkin is a naphthoquinone and racemic mixture of alkannin and shikonin that has been found in A. hispidissima.1

1.Singh, B., Sharma, M.K., Meghwal, P.R., et al.Anti-inflammatory activity of shikonin derivatives from Arnebia hispidissimaPhytomedicine10(5)375-380(2003)

Chemical Properties of Shikalkin

Cas No. 54952-43-1 SDF
المرادفات (±)-Alkannin, (±)-Shikonin, NSC 291845
Canonical SMILES O=C1C=C(C(C/C=C(C)/C)O)C(C2=C1C(O)=CC=C2O)=O
Formula C16H16O5 M.Wt 288.3
الذوبان DMF: 10 mg/ml,DMSO: 5 mg/ml,Ethanol: 1 mg/ml Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Shikalkin

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.4686 mL 17.343 mL 34.6861 mL
5 mM 693.7 μL 3.4686 mL 6.9372 mL
10 mM 346.9 μL 1.7343 mL 3.4686 mL
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In vivo Formulation Calculator (Clear solution) of Shikalkin

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Shikalkin

Average Rating: 5 ★★★★★ (Based on Reviews and 3 reference(s) in Google Scholar.)

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