Silver sulfadiazine |
| رقم الكتالوجGC61276 |
يؤثر سلفاديازين الفضة (AgSD) ، وهو مضاد حيوي للسلفوناميد ، على عمل مثبط مزدوج على نمو البكتيريا بواسطة جزء السلفا (SD-SDZ) الذي يمنع امتصاص الفولات البكتيري وتخليق الحمض النووي اللاحق
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 22199-08-2
Sample solution is provided at 25 µL, 10mM.
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Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication[1].
Silver sulfadiazine (AgSD) is a topical antibiotic used to the research of bacterial infection in burns[2].
[1]. Strydom SJ, et al. Poly(amidoamine) dendrimer-mediated synthesis and stabilization of silver sulfonamide nanoparticles with increased antibacterial activity. Nanomedicine. 2013;9(1):85-93. [2]. Munhoz DR, et al. Alginate films functionalized with silver sulfadiazine-loaded [Mg-Al] layered double hydroxide as antimicrobial wound dressing. Int J Biol Macromol. 2019;141:504-510.
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