Sisunatovir hydrochloride (Synonyms: RV521 hydrochloride) |
| رقم الكتالوجGC62217 |
يُظهر Sisunatovir (RV521) هيدروكلوريد ، وهو مثبط متاح عن طريق الفم لبروتين الانصهار RSV (RSV-F) ، فعالية قوية ضد مجموعة من العزلات السريرية لفيروسات RSV-A و RSV-B ، مع IC50s من 1.4 نانومتر و 1.0 نانومتر ، على التوالي
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1903763-83-6
Sample solution is provided at 25 µL, 10mM.
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Sisunatovir (RV521) hydrochloride, an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC50s of 1.4 nM and 1.0 nM, respectively[1].
[1]. DeVincenzo J, et al. A Randomized, Placebo-Controlled, Respiratory Syncytial Virus Human Challenge Study of the Antiviral Efficacy, Safety, and Pharmacokinetics of RV521, an Inhibitor of the RSV-F Protein. Antimicrob Agents Chemother. 2020;64(2):e01884-19. Published 2020 Jan 27.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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