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Solifenacin N-oxide

رقم الكتالوجGC44913 Copy One-Click Copy Product Info

Solifenacin N-oxide is an inactive metabolite of the muscarinic receptor antagonist solifenacin.

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Solifenacin N-oxide التركيب الكيميائي

Cas No.: 180272-28-0

الحجم السعر المخزون الكميّة
1mg
119٫00
متوفر
5mg
553٫00
متوفر
10mg
986٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.



Description of Solifenacin N-oxide

Solifenacin N-oxide is an inactive metabolite of the muscarinic receptor antagonist solifenacin . It is also a potential impurity found in commercial preparations of solifenacin. Solifenacin N-oxide is formed when solifenacin is stored under oxidative conditions.

Chemical Properties of Solifenacin N-oxide

Cas No. 180272-28-0 SDF
Canonical SMILES O=C(N1[C@@H](C2=CC=CC=C2)C3=CC=CC=C3CC1)O[C@@H](C4)C(CC5)CC[N]45=O
Formula C23H26N2O3 M.Wt 378.5
الذوبان DMF: 10 mg/ml,DMSO: 2 mg/ml,Ethanol: 15 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Solifenacin N-oxide

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.642 mL 13.21 mL 26.4201 mL
5 mM 528.4 μL 2.642 mL 5.284 mL
10 mM 264.2 μL 1.321 mL 2.642 mL
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In vivo Formulation Calculator (Clear solution) of Solifenacin N-oxide

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Solifenacin N-oxide

Average Rating: 5 ★★★★★ (Based on Reviews and 27 reference(s) in Google Scholar.)

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