SPR719 (Synonyms: VXc-486) |
| رقم الكتالوجGC61291 |
SPR719 (VXc-486) هو مثبط لل gyrase B ، مع نشاط مبيد للجراثيم
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Cas No.: 1384984-18-2
Sample solution is provided at 25 µL, 10mM.
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SPR719 (VXc-486) is a gyrase B inhibitor, with bactericidal activity. SPR719 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively[1].
[1]. Locher CP, et al. A novel inhibitor of gyrase B is a potent drug candidate for treatment of tuberculosis and nontuberculosis mycobacterial infections. Antimicrob Agents Chemother. 2015 Mar;59(3):1455-65.
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