SR18662 |
رقم الكتالوجGC39754 |
يعتبر SR18662 مثبطًا قويًا للعامل الخامس المشابه لـ KrÜppel (KLF5) مع IC50 من 4.4 نانومتر وتناظرية لـ ML264 مع فعالية مثبطة محسنة ضد خلايا سرطان القولون والمستقيميمكن استخدام SR18662 لدراسة سرطان القولون والمستقيم
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2505001-62-5
Sample solution is provided at 25 µL, 10mM.
SR18662 is a potent inhibitor of KrÜppel-like factor five (KLF5) with an IC50 of 4.4 nM, an analogue of ML264 with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer[1].
[1]. Julie Kim,et al.The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitroand In Vivo.Mol Cancer Ther.2019 Nov;18(11):1973-1984.
Average Rating: 5
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