Trans-Anethole ((E)-Anethole) (Synonyms: trans-Anethole, NSC 209529) |
| رقم الكتالوجGC32428 |
يُظهر Trans-Anethole ((E) -Anethole) ((E) -Anethole) ، وهو مشتق من فينيلبروبين معزول عن Pimpinella ، نشاطًا استروجينًا بتركيزات منخفضة وسامًا للخلايا بتركيزات أعلى في خطوط الخلايا السرطانية.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 4180-23-8
Sample solution is provided at 25 µL, 10mM.
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Trans-Anethole ((E)-Anethole), a phenylpropene derivative isolated from Pimpinella, shows estrogenic activity at lower concentrations and cytotoxic at higher concentrations in cancer cell lines[1][2]. Trans-Anethole ((E)-Anethole) contributes a large component of the odor and flavor of anise and fennel, anise myrtle, liquorice, camphor, magnolia blossoms, and star anise[3].
[1]. Tabanca N, et al. Estrogenic activity of isolated compounds and essential oils of Pimpinella species from Turkey, evaluated using a recombinant yeast screen. Planta Med. 2004 Aug;70(8):728-35. [2]. Nakagawa Y, et al. Cytotoxic and xenoestrogenic effects via biotransformation of trans-anethole on isolated rat hepatocytes and cultured MCF-7 human breast cancer cells. Biochem Pharmacol. 2003 Jul 1;66(1):63-73. [3]. Fahlbusch, et al. "Flavors and Fragrances", Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH.
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