(1S,2S,3R)-DT-061 |
| رقم الكتالوجGC34440 |
(1S ، 2S ، 3R) -DT-061 هو متماثل لـ DT-061DT-061 هو منشط متاح حيويًا عن طريق الفم لبروتين فوسفاتيز 2A (PP2A) ويمكن تطبيقه في علاج تكوّن الأورام المتحولة KRAS و MYC
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Cas No.: 1809427-20-0
Sample solution is provided at 25 µL, 10mM.
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(1S,2S,3R)-DT-061 is an enantiomer of DT-061. DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis[1].
[1]. Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.
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