(2S)-6-Prenylnaringenin (Synonyms: (2S)-6-PN) |
| رقم الكتالوجGC60000 |
(2S) -6-Prenylnaringenin هو المركب الأكثر فعالية في الدماغ الأمامي
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Cas No.: 68236-13-5
Sample solution is provided at 25 µL, 10mM.
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(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface[1].
(2S)-6-Prenylnaringenin (6-Prenylnaringenin) displays a modulatory activity at low micromolar concentrations. (2S)-6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner where the IC50 value for this potentiation in native GABAA receptors is 3.7 μM, respectively[1].
[1]. Ali Y Benkherouf, et al. Hops Compounds Modulatory Effects and 6-prenylnaringenin Dual Mode of Action on GABA AReceptors. Eur J Pharmacol. 2020 Apr 15;873:172962.
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