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(2S)-6-Prenylnaringenin (Synonyms: (2S)-6-PN)

カタログ番号GC60000

(2S)-6-プレニルナリンゲニンは、前脳で最も効率的な化合物です。

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(2S)-6-Prenylnaringenin 化学構造

Cas No.: 68236-13-5

サイズ 価格 在庫数 個数
1mg
$137.00
在庫あり
5mg
$342.00
在庫あり
10mg
$540.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface[1].

(2S)-6-Prenylnaringenin (6-Prenylnaringenin) displays a modulatory activity at low micromolar concentrations. (2S)-6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner where the IC50 value for this potentiation in native GABAA receptors is 3.7 μM, respectively[1].

[1]. Ali Y Benkherouf, et al. Hops Compounds Modulatory Effects and 6-prenylnaringenin Dual Mode of Action on GABA AReceptors. Eur J Pharmacol. 2020 Apr 15;873:172962.

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