3,4,5-Trihydroxycinnamic acid decyl ester |
| رقم الكتالوجGC61412 |
3،4،5-تريهيدروكسي سيناميك حمض ديسيل إستر هو مثبط ممتاز لامتصاص الدهون وتراكمها ، مع خصائص مضادة للسمنة
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1770778-45-4
Sample solution is provided at 25 µL, 10mM.
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3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM[1].
3,4,5-Trihydroxycinnamic acid decyl ester (30 μM) exhibits an inhibitory potency of approximately 92% for pancreatic lipase in vitro[1].3,4,5-Trihydroxycinnamic acid decyl ester (0.1-40 μM) inhibits pancreatic lipase activity in dose-dependent manner, with an EC50 value being approximately 0.9 μM[1].3,4,5-Trihydroxycinnamic acid decyl ester inhibits pancreatic lipase in vitro and lipid accumulation during 3T3-L1 cell differentiation[1].
3,4,5-Trihydroxycinnamic acid decyl ester (30-150 mg/kg; p.o.) suppresses a rise in blood triglyceride (TG) levels in mice given corn oil orally[1]. Animal Model: 6 weeks old Male ddY mice[1]
[1]. Masahiko Imai ,et al. Inhibitory effects of hydroxylated cinnamoyl esters on lipid absorption and accumulation. Bioorg Med Chem. 2015 Jul 1;23(13):3788-95.
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