β-D-glucuronide-pNP-carbonate |
| رقم الكتالوجGC66750 |
β ؛ -D-glucuronide-pNP-carbonate عبارة عن رابط ADC قابل للانقسام يستخدم في تخليق اقترانات الأجسام المضادة والأدوية (ADCs).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 894095-98-8
Sample solution is provided at 25 µL, 10mM.
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β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
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