BDP-13176 |
| رقم الكتالوجGC61612 |
BDP-13176 هو مثبط قوي لـ fascin 1 ، مع Kd 90 nM و IC50 لـ 240 nM. BDP-13176 لديه إمكانية كعامل مضاد للانتشار.
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Cas No.: 2290660-61-4
Sample solution is provided at 25 µL, 10mM.
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BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent[1].
BDP-13176 (0-1 μM) inhibits fascin 1 bundling activity[1].
[1]. Francis S, et al. Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg Med Chem Lett. 2019;29(8):1023-1029.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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