BeKm 1

Name: BeKm 1
Brand: GlpBio
SKU: GC50661
Availability: InStock
Rating: 5 (32 reviews)

رقم الكتالوجGC50661

BeKm 1 هو مركب مانع لـ HERG (الجين البشري المرتبط بالإيثر- a-go-go).

Products are for research use only. Not for human use. We do not sell to patients.

BeKm 1 التركيب الكيميائي

Cas No.: 524962-01-4

الحجم

السعر

المخزون

الكميّة

100ug

389٫00

متوفر

Tel：(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.

منتجات GlpBio المذكورة في الأوراق ذات السمعة الطيبة

Nature
610.7931 (2022): 366-372

Nature
618, 1017–1023 (2023)

Cell
183.7 (2020): 1867-1883

Cell Research
31, 1291–1307 (2021)

Cell Research
33, 273–287 (2023)

Cell Research
33, 546–561 (2023)

Molecular Cancer
21.1 (2022): 1-17

Molecular Cancer
21.1 (2022): 1-18

Cancer Cell
39 (2021): 1-16

Cell Host Microbe
30.8 (2022): 1124-1138

Cell Host Microbe
31.5 (2023): 766-780

Cell Host Microbe
31.3 (2023): 418-43

Cell Metabolism
34.2 (2022): 240-255

Ann Rheum Dis
82(4): 533-545 (2023)

Cell Mol Immunol
20, 264–276 (2023)

Adv Funct Mater
33.35 (2023): 2214998

Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >98.00%

Potent and selective KV11.1 (hERG) channel blocker. Selective for KV11.1 over a panel of 14 other potassium channels. Dose-dependently prolongs QTc interval in isolated rabbit heart.

Cas No.	524962-01-4	SDF
Canonical SMILES	[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]3CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N3)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC2=O)C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O)[C@@H](C)O
Formula	C174H261N51O52S6	M.Wt	4091.65
الذوبان		Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	0.2444 mL	1.222 mL	2.444 mL
	5 mM	0.0489 mL	0.2444 mL	0.4888 mL
	10 mM	0.0244 mL	0.1222 mL	0.2444 mL

حاسبة المولارية
حاسبة التخفيف

احسب

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal:μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

مراجعات

Review for BeKm 1

Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

5 Star

100%

4 Star

3 Star

2 Star

1 Star

Review for BeKm 1

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

Overall Rating

★

Review Title

المراجعة

اللقب

البريد الإلكتروني

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

BeKm 1

مراجعات العميل

GlpBio Citations

Bioactive Compounds Premium Provider

منتجات GlpBio المذكورة في الأوراق ذات السمعة الطيبة

Product Documents

Quality Control & SDS

Complete Stock Solution Preparation Table

حاسبة المولارية

حاسبة التخفيف

In vivo Formulation Calculator (Clear solution)

مراجعات

BeKm 1

مراجعات العميل

GlpBio Citations

Bioactive Compounds Premium Provider

منتجات GlpBio المذكورة في الأوراق ذات السمعة الطيبة

Product Documents

Quality Control & SDS

Complete Stock Solution Preparation Table

حاسبة المولارية

حاسبة التخفيف

In vivo Formulation Calculator (Clear solution)

Related Products

مراجعات