BET-IN-1 |
رقم الكتالوجGC31831 |
BET-IN-1 هو مثبط عموم لجميع نطاقات BET الثمانية ، والانتقائية على البروتينات التمثيلية الأخرى المحتوية على البرومودومين.
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Cas No.: 1422554-34-4
Sample solution is provided at 25 µL, 10mM.
BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1, compound example 2, has a plC50 in the range 6.0 - 7.0.IC50 value: 6.0 - 7.0 (plC50)Target: bromodomain
[1]. Demont Emmanuel Hubert, et al. Preparation of 4-(8-methoxy-1-(1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole, its salts and isomers and their use as bromodomain inhibitors. From PCT Int. Appl. (201
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