Apatinib Mesylate
A small chemical molecule, Apatinib Mesylate, also named YN968D1, is an orally administered antiangiogenic drug developed by Shanghai Hengrui Pharmaceutical, China. YN968D1 specifically inhibits vascular endothelial growth factor receptor-2 (VEGFR-2) tyrosine kinase. It blocks the pathways which lead to the downstream signalling of VEGFR-2 and reduces the density of cancer microvessels. When used against many experimental tumour models, Apatinib exhibits anticancer effectiveness. It prevents tumour angiogenesis by preventing the spread and development of vascular endothelial cells, it also inhibits other tyrosine kinases like c-Kit and c-Src.
Clozapine N-Oxide
The substance clozapine N-oxide (CNO) has recently come to light due to its application in pharmacology and neuroscience studies.
Trichostatin A
Trichostatin A (TSA) is a small molecule belonging to isohydroxamic acid. Its molecular structure showing its structural features is depicted in Figure 1.
Geneticin
Other names of Geneticin include G418 and G418 Sulphate. Pharmaceutically, Geneticin is an antibiotic belonging to the category of aminoglycoside. Aminoglycosides are the compounds having the amino group bounded to the sugar moiety. Its antibiotic effect, specifically the antiviral effect has been confirmed against bovine viral diarrhea virus (BVDV), dengue virus (DENV).
Px -478
Chemically, the full name of PX 478 is S-2-amino3-[4’-N, N,-bis(chloroethyl)amino]phenyl propionic acid N-oxide. It is a small molecule, i.e., having low atomicity and molecular weight. The 2D view of the molecular structure of the PX 478 compound is schematically depicted in Figure 1.
Cy 5.5 NHS ESTER
Chemically, Cy-5.5áN-hydroxysuccinamide ester is the full name of Cy 5.5 NHS ester. It is also known as cyanine 5.5 monosuccinimidyl ester. The Cy 5.5 NHS ester is a small molecule that implies that it has a low atomicity and also a low molecular weight.
The complete two-dimensional view of the molecular structure of the Cy 5.5 NHS ester compound is presented in the form of a schematic diagram in Figure 1.
Cl-Amidine
Chemically, N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide is the full name of Cl-Amidine. The Cl-Amidine molecule is small, i.e., low atomicity and thus low molecular weight. As its name suggests it is an amidine having a halo atom, i.e., chlorine. The two-dimensional view of the molecular structure of the Cl-Amidine compound is diagrammatically presented in Figure 1.
FK866
The full chemical name of the FK866 compound is (E)-N-[4-(1-benzoylpiperidin-4-yl) butyl]-3-(pyridin3-yl) acrylamide. It is also known as (E)-Daporinad and APO866 in the scientific literature. It is a small molecule with low molecular weight, artificially synthesized in laboratory and possess an entirely novel mechanism for its pharmaceutical action. A complete picture two-dimensional view of the molecular structure of the FK866 compound is presented in Figure 1.
OSMI 4
OSMI 4 is a small, synthetic and novel molecule. It has been discovered in a high-throughput screening (HTS) based on fluorescence luminescence. OSMI 4 is also known as OSMI-4b. The two-dimensional view of the Molecular structure of the OSMI 4 compound is diagrammatically depicted in Figure 1.