Bromfenac sodium hydrate |
| رقم الكتالوجGC35556 |
هيدرات الصوديوم برومفيناك (برومفيناك ملح أحادي الصوديوم سيسكويهيدرات) هو مثبط قوي وفعال عن طريق الفم لـ COX ، مع IC50s من 5.56 و 7.45 نانومتر لـ COX-1 و COX-2 ، على التوالي
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 120638-55-3
Sample solution is provided at 25 µL, 10mM.
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Bromfenac (sodium hydrate) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity(1) Bromfenac (sodium hydrate) (1 mg/kg, i.v.) is metabolited into an unusual conjugate, bromfenac N-glucoside, in rats bile(2) Bromfenac (sodium hydrate) permeation was found to be 1.62-fold higher through ChS-CS-NPs
[1]. Kirkman SK et al. Isolation and identification of bromfenac glucoside from rat bile. Drug Metab Dispos. 1998 Jul;26(7):720-3. [2]. Abdullah TA et al. Chondroitin sulfate-chitosan nanoparticles for ocular delivery of bromfenac sodium: Improved permeation, retention, and penetration. Int J Pharm Investig. 2016 Apr-Jun;6(2):96-105.
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